Controlled ErbB receptor dimerization

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GSE22288

Homo sapiens

12 Downloadable Samples

Affymetrix Human Gene 1.0 ST Array (hugene10st)

Submitter Supplied Information

Description

In order to better understand signaling events following receptor dimerization involving HER2, we have generated an experimental system in which ErbB dimerization can be controlled.

PubMed ID

21324925

Publication Title

Trastuzumab has preferential activity against breast cancers driven by HER2 homodimers.

Total Samples

Submitter’s Institution

Vanderbilt University

Authors

Ghosh R, Narasanna A, Wang SE, Liu S, Chakrabarty A, Balko JM, González-Angulo AM, Mills GB, Penuel E, Winslow J, Sperinde J, Dua R, Pidaparthi S, Mukherjee A, Leitzel K, Kostler WJ, Lipton A, Bates M, Arteaga CL

Source Repository

Gene Expression Omnibus (GEO)

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