Transcriptional changes in IL-2, IL-12 and IL-18 stimulated human natural killer cells

GSE22919

Homo sapiens

4 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

We used Affymetrix expression arrays to determine changes in gene expression associated with activation of human NK cells mediated through treatment with cytokines IL-2, IL-12 and IL-18 over a 24 hour period.

PubMed ID

20944005

Publication Title

PRDM1/Blimp-1 controls effector cytokine production in human NK cells.

Total Samples

Submitter’s Institution

Moffitt Cancer Center

Authors

Smith MA, Maurin M, Cho HI, Becknell B, Freud AG, Yu J, Wei S, Djeu J, Celis E, Caligiuri MA, Wright KL

Source Repository

Gene Expression Omnibus (GEO)

GSM565983

unstimulated_freshly_isolated_donor_2

male

30.000

natural killer cells

GSM565985

stimulated_24hr_donor_2

male

30.000

natural killer cells

GSM565982

unstimulated_freshly_isolated_donor_1

male

25.000

natural killer cells

GSM565984

stimulated_24hr_donor_1

male

25.000

natural killer cells