Induction and molecular signature of pathogenic Th17 cells

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GSE39820

Mus musculus

22 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

TGF-beta3 produced by developing Th17 cells induces highly pathogenic T cells that are functionally and molecularly distinct from TGF-beta1-induced Th17 cells. The microarray data represent a distinct molecular signature for pathogenic versus non-pathogenic Th17 cells.

PubMed ID

22961052

Publication Title

Induction and molecular signature of pathogenic TH17 cells.

Total Samples

Submitter’s Institution

Harvard Medical School/ Brigham Women's Hospital

Authors

Lee Y, Awasthi A, Yosef N, Quintana FJ, Xiao S, Peters A, Wu C, Kleinewietfeld M, Kunder S, Hafler DA, Sobel RA, Regev A, Kuchroo VK

Source Repository

Gene Expression Omnibus (GEO)

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