Integrating high-dimensional transcriptomics and image analysis tools into early safety screening (I)

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GSE70611

Homo sapiens

4 Downloadable Samples

Affymetrix Human Gene 1.1 ST Array (hugene11st)

Submitter Supplied Information

Description

In this paper we demonstrated the potential to flag toxicity issues by utilizing data from exploratory experiments which are typically generated for target evaluation purposes during early drug discovery

PubMed ID

25582842

Publication Title

Using transcriptomics to guide lead optimization in drug discovery projects: Lessons learned from the QSTAR project.

Total Samples

Submitter’s Institution

Janssen Pharmaceutica NV

Authors

Verbist B, Klambauer G, Vervoort L, Talloen W, QSTAR Consortium., Shkedy Z, Thas O, Bender A, Göhlmann HW, Hochreiter S

Source Repository

Gene Expression Omnibus (GEO)

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