Comparison of human PRDM12 mutants D31Y and E172D with wildtype fibroblasts

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SRP047363

Homo sapiens

4 Downloadable Samples

Illumina HiSeq 2000

Submitter Supplied Information

Description

Fibroblasts from PRDM12 patients and unaffected wildtype relatives were cultured until near confluency. The transcriptional profile of those cells was determined by mRNA sequencing and uncovered differential expression in several known pain and neurodevelopmental genes. Overall design: Transcriptome comparison of human PRDM12 mutant and wildtype fibroblasts

PubMed ID

25891934

Publication Title

The evolutionarily conserved transcription factor PRDM12 controls sensory neuron development and pain perception.

Total Samples

Submitter’s Institution

No associated institution

Authors

Nagy V, Cole T, Van Campenhout C, Khoung TM, Leung C, Vermeiren S, Novatchkova M, Wenzel D, Cikes D, Polyansky AA, Kozieradzki I, Meixner A, Bellefroid EJ, Neely GG, Penninger JM

Source Repository

Sequence Read Archive (SRA)

No rows found