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accession-icon GSE61643
PGC-1 Promotes Enterocyte Lifespan and Tumorigenesis in the Intestine
  • organism-icon Mus musculus
  • sample-icon 17 Downloadable Samples
  • Technology Badge IconIllumina MouseRef-8 v2.0 expression beadchip

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

PGC-1β promotes enterocyte lifespan and tumorigenesis in the intestine.

Sample Metadata Fields

Specimen part

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accession-icon GSE61642
Genome-wide analysis expression of ileum tumor samples from FVBN/APCmin and iPGC-1/APCmin
  • organism-icon Mus musculus
  • sample-icon 12 Downloadable Samples
  • Technology Badge IconIllumina MouseRef-8 v2.0 expression beadchip

Description

Analysis of metabolic pathway gene expression. The hypothesis tested in the present study is to assess mRNA level changes in metabolic genes in intestinal tumors from APCmin mice overexpressing PGC-1 specifically in the intestine.

Publication Title

PGC-1β promotes enterocyte lifespan and tumorigenesis in the intestine.

Sample Metadata Fields

Specimen part

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accession-icon GSE61640
Genome-wide analysis expression of ileum samples from PGC-1 fl/? and iKOPGC-1
  • organism-icon Mus musculus
  • sample-icon 5 Downloadable Samples
  • Technology Badge IconIllumina MouseRef-8 v2.0 expression beadchip

Description

Analysis of metabolic pathway gene expression. The hypothesis tested in the present study is to assess mRNA level changes in metabolic genes in enterocytes from intestine specific PGC-1 konckout mice.

Publication Title

PGC-1β promotes enterocyte lifespan and tumorigenesis in the intestine.

Sample Metadata Fields

Specimen part

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accession-icon GSE44073
Liver X Receptors play an antitumoral role in the intestine
  • organism-icon Mus musculus, Homo sapiens
  • sample-icon 16 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V4.0 expression beadchip, Illumina MouseRef-8 v2.0 expression beadchip

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Liver X receptors inhibit proliferation of human colorectal cancer cells and growth of intestinal tumors in mice.

Sample Metadata Fields

Age, Specimen part

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accession-icon GSE44071
Genome-wide analysis of gene expression profile of Intestinal (ILEUM) Tumors from APCmin/+/VP16LXRa vs APCmin/+/VP16
  • organism-icon Mus musculus
  • sample-icon 8 Downloadable Samples
  • Technology Badge IconIllumina MouseRef-8 v2.0 expression beadchip

Description

Changes in gene expression profile of intestinal (ILEUM) Tumors from APCmin/+/VP16LXRa vs APCmin/+/VP16. The hypothesis tested in the present study was that LXRa overexpression influence cancer growth modulating lipid metabolism in cancer cells. Results provide the information that LXRa induces genes encoding proteins able to regulate cholesterol efflux.

Publication Title

Liver X receptors inhibit proliferation of human colorectal cancer cells and growth of intestinal tumors in mice.

Sample Metadata Fields

Age, Specimen part

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accession-icon GSE64566
GE/miRNA expression profile of Human Epicardial Adipose Tissue (EAT) and Subcutaneous Adipose Tissue (SAT) in Patients with Coronary Artery Disease (CAD) vs. Controls (CTRL)
  • organism-icon Homo sapiens
  • sample-icon 29 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V3.0 expression beadchip

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Integrative miRNA and whole-genome analyses of epicardial adipose tissue in patients with coronary atherosclerosis.

Sample Metadata Fields

Age, Specimen part, Disease, Disease stage

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accession-icon GSE64554
GE/miRNA expression profile of Human Epicardial Adipose Tissue (EAT) and Subcutaneous Adipose Tissue (SAT) in Patients with Coronary Artery Disease (CAD) vs. Controls (CTRL) - PART 1 - Genes
  • organism-icon Homo sapiens
  • sample-icon 29 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V3.0 expression beadchip

Description

Gene expression profiles of Human EAT vs. SAT (CTRL & CAD). The aim of the present study was to assess a gene expression chart characterizing EAT vs. SAT, and CAD vs. CTRL. Results provide the information that EAT is characterized by a differential expression of different genes when compared to its reference tissue (SAT), and that EAT is characterized by specific gene expression changes in patients with CAD.

Publication Title

Integrative miRNA and whole-genome analyses of epicardial adipose tissue in patients with coronary atherosclerosis.

Sample Metadata Fields

Age, Specimen part, Disease, Disease stage

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accession-icon GSE62980
Expression data from mice after knockout or overexpression of Tcfeb in muscle
  • organism-icon Mus musculus
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430A 2.0 Array (mouse430a2)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Transcription Factor EB Controls Metabolic Flexibility during Exercise.

Sample Metadata Fields

Age, Specimen part

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accession-icon GSE62976
Expression data from Tcfeb KO mice specifically in muscle
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430A 2.0 Array (mouse430a2)

Description

In order to identify the effects of the absence of Tcfeb on the muscle transcriptome, we performed Affymetrix Gene-Chip hybridization experiments for the KO mice as compared with wt mice

Publication Title

Transcription Factor EB Controls Metabolic Flexibility during Exercise.

Sample Metadata Fields

Age, Specimen part

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