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accession-icon SRP183071
GOYA DLBCL clinical trial - RNASeq dataset
  • organism-icon Homo sapiens
  • sample-icon 502 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

This dataset contains collected RNASeq data of 552 samples from the GOYA clinical trial. Overall design: The GOYA trial tested the efficacy of Gazyva (GA101) compared with Rituxan (Rituximab) in first line, untreated DLBCL patients. Patients were randomized 1:1 to either G or R combined with a CHOP chemotherapy backbone. Tumor samples were collected at baseline, RNA was isolated using RNA-Access, and RNASeq was run with TruSeq (Illumina) RNASeq.

Publication Title

PD-L1 and tumor-associated macrophages in de novo DLBCL.

Sample Metadata Fields

Treatment, Subject

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accession-icon GSE8391
Clockwork Orange is a transcriptional repressor and a new Drosophila circadian pacemaker component
  • organism-icon Drosophila melanogaster
  • sample-icon 33 Downloadable Samples
  • Technology Badge Icon Affymetrix Drosophila Genome 2.0 Array (drosophila2), Affymetrix Drosophila Genome Array (drosgenome1)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Clockwork Orange is a transcriptional repressor and a new Drosophila circadian pacemaker component.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE7646
CLK targets from fly heads
  • organism-icon Drosophila melanogaster
  • sample-icon 4 Downloadable Samples
  • Technology Badge Icon Affymetrix Drosophila Genome Array (drosgenome1)

Description

CLK targets from fly heads using the TIM-GAL4; UAS-CLKGR line

Publication Title

Clockwork Orange is a transcriptional repressor and a new Drosophila circadian pacemaker component.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE7652
Timepoints Control strain
  • organism-icon Drosophila melanogaster
  • sample-icon 10 Downloadable Samples
  • Technology Badge Icon Affymetrix Drosophila Genome 2.0 Array (drosophila2)

Description

6 Timepoint microarray from control strain

Publication Title

Clockwork Orange is a transcriptional repressor and a new Drosophila circadian pacemaker component.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE7651
Timepoints 5073 strain
  • organism-icon Drosophila melanogaster
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Drosophila Genome 2.0 Array (drosophila2)

Description

6 Timepoints from 5073 strain

Publication Title

Clockwork Orange is a transcriptional repressor and a new Drosophila circadian pacemaker component.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE7644
CLKGR in S2 cells
  • organism-icon Drosophila melanogaster
  • sample-icon 4 Downloadable Samples
  • Technology Badge Icon Affymetrix Drosophila Genome Array (drosgenome1)

Description

Experiments performed in S2 cells to identify direct CLK targets

Publication Title

Clockwork Orange is a transcriptional repressor and a new Drosophila circadian pacemaker component.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE7653
S2 cells transfected with Clk
  • organism-icon Drosophila melanogaster
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Drosophila Genome 2.0 Array (drosophila2)

Description

S2 cells transfected with pAc-Clk or empty vector

Publication Title

Clockwork Orange is a transcriptional repressor and a new Drosophila circadian pacemaker component.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE30143
Gene expression profiling in lungs of mice with mesenchyme-specific GR ablation (GRCol1-Cre)
  • organism-icon Mus musculus
  • sample-icon 20 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430A 2.0 Array (mouse430a2)

Description

The goal of the experiment was to assay the role of the glucocorticoid receptor (GR) in development of mesenchynmal cells of the lung occuring between the 16 and 18 day of embryonal development.

Publication Title

Glucocorticoid activity during lung maturation is essential in mesenchymal and less in alveolar epithelial cells.

Sample Metadata Fields

Specimen part

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accession-icon GSE2422
WT Vs TIM-MJD
  • organism-icon Drosophila melanogaster
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Drosophila Genome Array (drosgenome1)

Description

WT flies or flies of the strain Tim-gal4; UAS-MJD78Q. All samples were collected at ZT16 after 3 days of training in LD conditions.

Publication Title

Neurotoxic protein expression reveals connections between the circadian clock and mating behavior in Drosophila.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE63164
Expression data from Zeb1 knockdown NM18 cells
  • organism-icon Mus musculus
  • sample-icon 3 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Expression 430A Array (moe430a)

Description

Differentiation of epithelial cells is strongly affected by transcription factors related to epithelial to mesenchymal-like progression.

Publication Title

Zeb1 affects epithelial cell adhesion by diverting glycosphingolipid metabolism.

Sample Metadata Fields

Specimen part, Cell line

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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