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accession-icon GSE38222
Stau2 RIP-Chip in Mouse E13-14 Cortex
  • organism-icon Mus musculus
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Description

The double-stranded RNA binding protein Staufen2 (Stau2) is asymmetrically localized and segregated during asymmetric cell divisions in the developing mouse cortex and promotes intermediate progenitor cell fate.

Publication Title

Asymmetric segregation of the double-stranded RNA binding protein Staufen2 during mammalian neural stem cell divisions promotes lineage progression.

Sample Metadata Fields

Specimen part

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accession-icon E-MEXP-749
Transcription profiling by array of Arabidopsis after treatment with benzyladenine
  • organism-icon Arabidopsis thaliana
  • sample-icon 13 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis Genome Array (ag)

Description

10 day old seedlings were treated with 5uM of the cytokinin Benzyladenine(BA)or DMSO at 15min, 45min, 120min, 480min and 1440min

Publication Title

Expression profiling of cytokinin action in Arabidopsis.

Sample Metadata Fields

Age, Compound, Time

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accession-icon GSE19978
Different gene expressions in root tips between CLE10 and CLE25 treatment
  • organism-icon Arabidopsis thaliana
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Cellcell communication is critical for tissue and organ development. In plants, secretory CLAVATA3/EMBRYO SURROUNDING REGION-related (CLE) peptides function as intercellular signaling molecules in various aspects of tissue development. However, little is known about intracellular signaling pathways functioning in vascular development downstream of the CLE ligands. To elucidate CLE signaling pathway, we performed GeneChip analysis.

Publication Title

CLE peptides can negatively regulate protoxylem vessel formation via cytokinin signaling.

Sample Metadata Fields

Specimen part

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accession-icon E-MEXP-432
Transcription profiling of inducible overexpression of Arabidopsis meristem regulators by AlcR / AlcA system in continuous light
  • organism-icon Arabidopsis thaliana
  • sample-icon 10 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Inducible overexpression of Arabidopsis meristem regulators by AlcR / AlcA system. Plants harboring 35S::AlcR/AlcA::GOI (GUS control, LEAFY, SHOOTMERSTEMLESS, WUSCHEL)constructs were grown in continous light for 12 days and induced with 1% Ethanol. After 12h of EtOH treatment, seedlings were dissected and RNA was processed from the shoot apex and young leaves. Affymetrix Ath1 arrays were hybridized in duplicates from each experiment.

Publication Title

WUSCHEL controls meristem function by direct regulation of cytokinin-inducible response regulators.

Sample Metadata Fields

Age, Specimen part, Subject, Compound

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accession-icon E-MTAB-1596
Transcription profiling by array of Arabidopsis seedlings grown in constant light with or without benzyladenine treatment
  • organism-icon Arabidopsis thaliana
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Aim of this experiment was to look at the gene expression differences in the benzyladenine-treated and untreated Arabidopsis seedlings grown in light

Publication Title

Identification of cytokinin-responsive genes using microarray meta-analysis and RNA-Seq in Arabidopsis.

Sample Metadata Fields

Age, Specimen part, Compound

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accession-icon E-MTAB-1601
Transcription profiling by array of Arabidopsis seedlings grown in light with or without benzyladenine or Zeatin treatment
  • organism-icon Arabidopsis thaliana
  • sample-icon 3 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Aim was to look at the gene profile changes in 10 days old Arabidopsis seedlings grown in light and treated with either Zeatin or BA and compared to non-treatment

Publication Title

Identification of cytokinin-responsive genes using microarray meta-analysis and RNA-Seq in Arabidopsis.

Sample Metadata Fields

Age, Compound

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accession-icon SRP115534
RNA-seq of genes mis-regulated in WT and the bpc1,2,3,4,6 loss-of-function mutant in response to cytokinin in roots of Arabidopsis thaliana
  • organism-icon Arabidopsis thaliana
  • sample-icon 12 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2500

Description

We find that sub-set of cytokin repsonse genes are not regulated at WT levels in the bpc1,2,3,4,6 mutant. Overall design: Whole ten-day-old seedlings of WT and the bpc1,2,3,4,6 mutant were treated with synthetic cytokinin (benzyladenine) or a vehicle control (NaOH) for 1 hour and root tissue was isolated.

Publication Title

Role of BASIC PENTACYSTEINE transcription factors in a subset of cytokinin signaling responses.

Sample Metadata Fields

Specimen part, Treatment, Subject

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accession-icon GSE54870
Transcription profiling by array of wild type and arr1,10,12 mutant Arabidopsis seedlings treated with the cytokinin benzyladenine
  • organism-icon Arabidopsis thaliana
  • sample-icon 8 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Effect of the cytokinin BA on wt and arr1,10,12 mutant seedlings

Publication Title

Type B response regulators of Arabidopsis play key roles in cytokinin signaling and plant development.

Sample Metadata Fields

Age, Specimen part

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accession-icon GSE11812
Gene expression profile of cancer cell lines of different origin
  • organism-icon Homo sapiens
  • sample-icon 30 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A Array (hgu133a)

Description

Gene expression profile of cancer cell lines of breast, lung, pancreatic, gasctric, ovarian, hepatocellular, prostate carcinomas and melanomas.

Publication Title

Gene expression profiling of 30 cancer cell lines predicts resistance towards 11 anticancer drugs at clinically achieved concentrations.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE79485
Expression data of differentially regualted genes in TH-MYCN mouse tumors after immunotherapy
  • organism-icon Mus musculus
  • sample-icon 16 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Gene 2.1 ST Array (mogene21st)

Description

In order to understand differentially regulated gene expression after the different treatments, 4 size matched tumors of each group were analyzed by microarrays.

Publication Title

Regulation of myeloid cells by activated T cells determines the efficacy of PD-1 blockade.

Sample Metadata Fields

Specimen part

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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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