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accession-icon SRP070915
Homo sapiens Transcriptome or Gene expression
  • organism-icon Homo sapiens
  • sample-icon 5 Downloadable Samples
  • Technology Badge IconIlluminaHiSeq2500

Description

we characterized the small RNA content of exosomes derived from gastric cancer cell lines by deep sequencing

Publication Title

No associated publication

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon SRP078083
Single cell RNA-seq analysis of a squamous cell carcinoma of urinary bladder
  • organism-icon Homo sapiens
  • sample-icon 95 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

We use single cell RNA-seq method to analysis the transcriptional heterogeneity in squamous cell carcinoma of urinary bladder. The single cell sequencing approach is based on the method of single-cell tagged reverse transcription (STRT).

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part

View Samples
accession-icon SRP101761
RNA-seq identifies ß-estradiol treatment in U2OS osteosarcoma cell
  • organism-icon Homo sapiens
  • sample-icon 5 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

This study was to identify gene expression profile change associated withß-estradiol treatment in osteosarcoma cells by high-throughput RNA sequencing

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Cell line

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accession-icon SRP095590
RNA-sequencing celecoxib-treated lung squamous cell carcinoma cell line
  • organism-icon Homo sapiens
  • sample-icon 4 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

Celecoxib is an inhibitor of cyclooxygenase-2-incuced lung squamous cell carcinoma (LSQCC). The study aims to provide novel insight into celecoxib’s chemoprevention

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Cell line

View Samples
accession-icon GSE25436
Expression data from melanoma cell lines
  • organism-icon Homo sapiens
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Differential gene expression analysis of parental and sub-lines of melanoma cell line resistant to F5 CTL lymphocyte

Publication Title

Molecular mechanism of MART-1+/A*0201+ human melanoma resistance to specific CTL-killing despite functional tumor-CTL interaction.

Sample Metadata Fields

Cell line

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accession-icon E-MEXP-1287
Transcription profiling by array of Drosophila melanogaster inoculated with P.aeruginosa or mechanically injured to investigate the skeletal muscle regulatory network in response to wound infection following trauma
  • organism-icon Drosophila melanogaster
  • sample-icon 4 Downloadable Samples
  • Technology Badge Icon Affymetrix Drosophila Genome Array (drosgenome1)

Description

Effect of injury and Pseudomonas aeruginosa inoculation in Drosophila melanogaster

Publication Title

Involvement of skeletal muscle gene regulatory network in susceptibility to wound infection following trauma.

Sample Metadata Fields

Sex, Time

View Samples
accession-icon SRP158937
NICD2 overexpression in the bone marrow stromal cell line ST-2 cells
  • organism-icon Mus musculus
  • sample-icon 2 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 2000

Description

Notch signaling critically controls cell fate decisions in mammals, both during embryogenesis and in adults. In the skeleton, Notch suppresses osteoblast differentiation and sustains bone marrow mesenchymal progenitors during postnatal life. Stabilizing mutations of Notch2 cause the Hajdu-Cheney syndrome characterized by early onset osteoporosis in humans, but the mechanism whereby Notch inhibits bone accretion is not fully understood.To gain further insights about the mechanism we performed RNA-seq experiments with the doxycycline-inducible NICD2-ST2 cells with or without doxycycline treatment for 24 hrs.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part, Cell line, Treatment

View Samples
accession-icon E-MTAB-2220
mouse hepatic gene whole transcript expression
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Gene 2.0 ST Array (mogene20st)

Description

Whole transcript expression analysis was performed on liver biopsy from wild mice,DEN model mice and cell-treated mice(2 mice per group)

Publication Title

Transplantation of periportal vessel stem cells promotes liver injury repair in cirrhotic mice

Sample Metadata Fields

Age, Specimen part

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accession-icon GSE97779
Expression data from rheumatoid arthritis synovial macrophages
  • organism-icon Homo sapiens
  • sample-icon 14 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Macrophages from RA synovial fluids were compared to primary human monocyte-derived macrophages.

Publication Title

Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF.

Sample Metadata Fields

Specimen part, Disease stage, Subject

View Samples
accession-icon GSE11864
Effect of interferon-gamma on macrophage differentiation and response to Toll-like receptor ligands
  • organism-icon Homo sapiens
  • sample-icon 10 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Gene expression analysis of freshly isolated CD14+ human monocytes and monocytes cultured in the presence or absence of interferon (IFN) -gamma for 24 h and then stimulated with Pam3Cys, a Toll-like receptor (TLR) 2 ligand, for 6 h. Results provide insight into mechanisms by which IFN-gamma reprograms early macrophage differentiation and subsequent response to TLR ligands.

Publication Title

Integrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways.

Sample Metadata Fields

No sample metadata fields

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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