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accession-icon GSE10880
Expression profiling of MRC5, IFN gamma treated MRC5 and PGF cells.
  • organism-icon Homo sapiens
  • sample-icon 3 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Expression profiling of MRC5, IFN gamma treated MRC5 and PGF cells.

Publication Title

Reconfiguration of genomic anchors upon transcriptional activation of the human major histocompatibility complex.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE27928
Characterization of gene expression of tumor infiltrating T cells (TILs) in previously untreated patients with follicular lymphoma (FL) compared with those of tonsils
  • organism-icon Homo sapiens
  • sample-icon 35 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

It has been shown that tumor infiltrating immune cells have a profound impact on the outcome of FL. To find mechanisms whereby TILs are altered gene expession analysis of highly pure TILs were performed.

Publication Title

Follicular lymphoma cells induce changes in T-cell gene expression and function: potential impact on survival and risk of transformation.

Sample Metadata Fields

Specimen part, Subject

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accession-icon GSE94279
Expression data from environmentally enriched mice
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Gene 2.0 ST Array (mogene20st)

Description

Environmental enrichment has been shown to induce wholescale alterations to the gene expression profile of experimental animals

Publication Title

The impact of environmental enrichment on the murine inflammatory immune response.

Sample Metadata Fields

Sex, Age

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accession-icon GSE13610
Basal gene expression in bone (mice and rat)
  • organism-icon Mus musculus, Rattus norvegicus
  • sample-icon 15 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Adult rat bones maintain distinct regionalized expression of markers associated with their development.

Sample Metadata Fields

Sex, Specimen part, Treatment

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accession-icon GSE12966
Basal gene expression in bone
  • organism-icon Rattus norvegicus
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Analysis of basal gene expression of the protective bones of the skull (parietals) and weight-bearing bones of the limb (ulnae)

Publication Title

Adult rat bones maintain distinct regionalized expression of markers associated with their development.

Sample Metadata Fields

Sex, Specimen part, Treatment

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accession-icon GSE13563
Pilot study: Basal gene expression in bone
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Description

Pilot study

Publication Title

Adult rat bones maintain distinct regionalized expression of markers associated with their development.

Sample Metadata Fields

Sex, Specimen part

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accession-icon GSE42288
Comparative molecular assessment of implant adherent cells in smokers and non-smokers
  • organism-icon Homo sapiens
  • sample-icon 83 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.1 ST Array (hugene11st)

Description

Objective: to Identify the effect of surface texture on the modulation of gene transcription of implant adherent cells as influenced by the smoking habits of the subjects.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part, Subject

View Samples
accession-icon GSE41446
Early molecular assessment of osseointegration in humans
  • organism-icon Homo sapiens
  • sample-icon 42 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.1 ST Array (hugene11st)

Description

To determine the early temporal wide genome transcription regulation by the surface topography at the bone-implant interface of implants bearing micro-roughened or superimposed nanosurface topology.

Publication Title

No associated publication

Sample Metadata Fields

Sex

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accession-icon GSE35976
Genome wide array analysis of endosseous implant adherent cellular phenotypes
  • organism-icon Rattus norvegicus
  • sample-icon 16 Downloadable Samples
  • Technology Badge Icon Affymetrix Rat Gene 1.1 ST Array (ragene11st)

Description

Objective: to identify the early molecular processes involved in osseointegration associated with a micro roughened and nanosurface featured implants.

Publication Title

Comparative molecular assessment of early osseointegration in implant-adherent cells.

Sample Metadata Fields

Sex, Specimen part

View Samples
accession-icon GSE77459
Gene Expression Profile of Pulpitis
  • organism-icon Homo sapiens
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 2.1 ST Array (hugene21st)

Description

This study was aimed to identify the genetic contributors to pulpal pain and inflammation. Inflamed pulps were collected from patients diagnosed with irreversible pulpitis (n=6). Normal pulps from teeth extracted for various reasons served as controls (n=6). Pain level was assessed using a visual analog scale (VAS). Genome-wide microarray analysis was performed using Affymetrix GeneTitan Multichannel Instrument. The difference in gene expression levels were determined by the Significance Analysis of Microarray program using a false discovery rate (q-value) of 5%. Genes involved in immune response, cytokine-cytokine receptor interaction and signaling, integrin cell surface interactions, and others were expressed at relatively higher levels in the pulpitis group. Moreover, several genes known to modulate pain and inflammation showed differential expression in asymptomatic and mild pain patients compared to those with moderate to severe pain(>30mm on VAS). This exploratory study provides a molecular basis for the clinical diagnosis of pulpitis. With an enhanced understanding of pulpal inflammation, future studies on treatment and management of pulpitis and on pain associated with it can have a biological reference to bridge treatment strategies with pulpal biology.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part, Disease

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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