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accession-icon GSE29901
Retinal whole genome microarray analysis after irradiated injury of intraorbital nerve in the monkey
  • organism-icon Macaca mulatta
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Rhesus Macaque Genome Array (rhesus)

Description

To obtain and analyze early retinal changes at molecular level at 24h after ipsilateral intraorbital nerve radiation injury by gamma knife surgery

Publication Title

Retinal whole genome microarray analysis and early morphological changes in the optic nerves of monkeys after an intraorbital nerve irradiated injury.

Sample Metadata Fields

Specimen part, Treatment

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accession-icon GSE119143
Expression data of lncRNAs and mRNAs extracted from PBMCs of tuberculosis patients and healthy individuals[HTA2.0]
  • organism-icon Homo sapiens
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Transcriptome Array 2.0 (hta20)

Description

Tuberculosis (TB) is the ninth leading cause of death worldwide and the leading cause from a single infectious agent, ranking above HIV/AIDS.Although considerable advances have been achieved in recent years, the genetic and molecular mechanisms underlying this disease remain largely unclear.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part, Disease stage

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accession-icon GSE84609
Effect of GDF11 on RANKL-induced osteoclastogenesis
  • organism-icon Mus musculus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Description

GDF11 treatment leads to bone loss in mice and strongly stimulates RANKL-induced osteoclastogenesis of bone marrowderived macrophages (BMMs) in vitro.

Publication Title

GDF11 decreases bone mass by stimulating osteoclastogenesis and inhibiting osteoblast differentiation.

Sample Metadata Fields

Specimen part, Treatment

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accession-icon GSE145781
Whole spleen transcriptome during acute phase of infection in a virulent Plasmodium chabaudi chabaudi CB infection
  • organism-icon Mus musculus
  • sample-icon 32 Downloadable Samples
  • Technology Badge IconIllumina MouseWG-6 v2.0 expression beadchip

Description

Analysis of spleen samples taken throughout the acute phase of infection from mice infected with virulent P. chabaudi CB strain

Publication Title

Transcriptome analysis of blood and spleen in virulent and avirulent mouse malaria infection.

Sample Metadata Fields

Sex, Specimen part, Time

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accession-icon GSE145634
Rodent malaria parasite RNA does not affect mouse BeadChip results
  • organism-icon Mus musculus, Plasmodium chabaudi
  • sample-icon 8 Downloadable Samples
  • Technology Badge IconIllumina MouseWG-6 v2.0 expression beadchip

Description

Rodent malaria parasite RNA hybridized on Illumina Mouse WG-6 v2.0 Expression BeadChip

Publication Title

Transcriptome analysis of blood and spleen in virulent and avirulent mouse malaria infection.

Sample Metadata Fields

Sex, Specimen part

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accession-icon SRP152744
Homo sapiens Transcriptome or Gene expression
  • organism-icon Homo sapiens
  • sample-icon 12 Downloadable Samples
  • Technology Badge IconIllumina HiSeq 4000

Description

RNA-sequencings of TSPY1-overexpressed A549 and HepG2 cells were performed to systematically explore the signaling pathways in which TSPY1 is involved during tumor progression.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part, Cell line, Treatment

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accession-icon GSE80822
Comparative transcriptomes reveal novel evolutionary strategies adopted by Saccharomyces cerevisiae with improved xylose utilization capability
  • organism-icon Saccharomyces cerevisiae
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Yeast Genome 2.0 Array (yeast2)

Description

The xylose fermentation capability of an industrainl Saccharomyces cerevisiae strain was enhanced by adaptive evolution. Eight homozygots were generated by tetrads dissection.

Publication Title

Comparative transcriptomes reveal novel evolutionary strategies adopted by Saccharomyces cerevisiae with improved xylose utilization capability.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE80748
Transcriptomes of a xylose-utilizing industrial flocculating Saccharomyces cerevisiae strain cultured in media containing different sugar sources
  • organism-icon Saccharomyces cerevisiae
  • sample-icon 8 Downloadable Samples
  • Technology Badge Icon Affymetrix Yeast Genome 2.0 Array (yeast2)

Description

The molecular basis for glucose and xylose fermentation by industrial Saccharomyces cerevisiae is of interest to promote bioethanol production

Publication Title

Transcriptomes of a xylose-utilizing industrial flocculating Saccharomyces cerevisiae strain cultured in media containing different sugar sources.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE29212
MicroRNA Profiles and Their Control of Male Gametophyte Development in Rice
  • organism-icon Oryza sativa indica group
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Rice Genome Array (rice)

Description

Plant microRNAs (miRNAs) act as negative regulators of gene expression by slicing target transcripts or inhibiting the translation, and a number of miRNAs play important roles in development. In order to investigate the potential function of miRNAs during male gametogenesis in rice, we obtained both gene and small RNA expression profiles by combining Affymetrix microarray and high-throughput sequencing technologies. In genome-scale, we compared arrays and sRNA-Seq datasets in different stages/organs of rice by applying computational and statistical approaches.

Publication Title

MicroRNA profiles and their control of male gametophyte development in rice.

Sample Metadata Fields

Specimen part

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accession-icon GSE119796
Expression data of genes and noncoding genes from the ADSCs and adipogenic-induced ADSCs
  • organism-icon Rattus norvegicus
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Rat Gene 2.0 ST Array (ragene20st)

Description

Adipogenesis participates in many physiological and pathological processes such as obesity and diabetes, and is regulated by a series of precise molecular events. However, the molecules involved in this regulation have not been fully characterized.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Specimen part

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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